Fast and accurate dose predictions for novel radiotherapy treatments in heterogeneous phantoms using conditional 3D-UNet generative adversarial networks

develop a generative adversarial network (GAN) model, which is able to emulate the equivalent Geant4 Monte Carlo simulation with adequate accuracy, and use it to predict the radiation dose delivered by [...] phantoms. Methods: The energy depositions used for the training of the GAN are obtained using full Geant4 Monte Carlo simulations of a synchrotron radiation broad beam passing through the phantoms. The energy [...] dimensions. The computing time for a single prediction is reduced from several hundred hours using Geant4 simulation to less than a second using the GAN model. Conclusions: The proposed GAN model predicts dose …