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GRK 2624
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Research
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Projects
P5: ExpTimeDose-DoE
models developed in project P2 and P3. References Dette H, Kiss C, Bevanda M, Bretz F (2010). Optimal designs for emax, log-linear and exponential models. Biometrika 97 (2), 513-518, doi: 10.1093/biomet/asq020 [...] time-dose curves In project P5, optimal designs will be derived for the models developed in projects P2 and P3, respectively. It is well known that optimal design of experiments can substantially improve [...] dependent time data. Finally, we will extend these results to the models developed in the projects P2 and P3. Since these models will be complex, the optimal designs according to the developed criteria …